N-(1-金刚烷)甲酰胺合成路线 （共 19 条）
反应条件
2,2'-azo-bisisobutyronitrile; hypophosphorous ether; triethylamine in 1,4-dioxane 1.5 h;
参考文献
Barton; Jang; Jaszberenyi
Tetrahedron Letters, 1992 , vol. 33, # 39 p. 5709 - 5712
反应条件
sulfuric acid; tert-butyl alcohol in hexane
参考文献
Haaf,W.
Chemische Berichte, 1964 , vol. 97, p. 3234 - 3240
反应条件
2,2'-azo-bisisobutyronitrile; hypophosphorous ether; triethylamine in 1,4-dioxane; water 1.5 h; Heatingvarious reaction conditions; also for other 1-substituted adamantanes; Product distribution;
参考文献
Barton, Derek H. R.; Jang, Doo Ok; Jaszberenyi, Joseph Cs.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6838 - 6842
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Sasaki, Tadashi; Nakanishi, Akira; Ohno, Masatomi
Journal of Organic Chemistry, 1981 , vol. 46, # 26 p. 5445 - 5447
反应条件
(i) NaCN, H2SO4, (ii) H2O; Multistep reaction;
参考文献
Haaf,W.
Chemische Berichte, 1963 , vol. 96, p. 3359 - 3369
反应条件
lithium aluminium tetrahydride
参考文献
Marrazzo, Agostino; Prezzavento, Orazio; Pasquinucci, Lorella; Vittorio, Franco; Ronsisvalle, Giuseppe
Farmaco, 2001 , vol. 56, # 3 p. 181 - 189
反应条件
triethylamine; trichlorophosphate in dichloromethane
参考文献
Gravestock, David; Rousseau, Amanda L.; Lourens, Anna C.U.; Hoppe, Heinrich C.; Nkabinde, Lindiwe A.; Bode, Moira L.
Tetrahedron Letters, 2012 , vol. 53, # 26 p. 3225 - 3229
反应条件
1: phosphoroyl chloride, Et3N / CH2Cl2 / 24 h / Ambient temperature 2: 100 percent / Ph2SiH2, benzoyl peroxide / dioxane / 1 h / Heating View Scheme
参考文献
Barton, Derek H. R.; Jang, Doo Ok; Jaszberenyi, Joseph Cs.
Tetrahedron, 1993 , vol. 49, # 33 p. 7193 - 7214
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=40°C; Reduction; 5 h;
参考文献
Ronsisvalle, Giuseppe; Marrazzo, Agostino; Prezzavento, Orazio; Pasquinucci, Lorella; Falcucci, Barbara; Di Toro, Rosanna; Spampinato, Santi
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 6 p. 1503 - 1513
