反应条件
1.1: LHMDS / tetrahydrofuran / -15 °C 2.1: BnMe3NOH; NaOH / dioxane / 45 °C 2.2: aq. HCl / 50 °C 3.1: tBuCOCl / tetrahydrofuran / 0 - 10 °C 4.1: TsOH*H2O / methanol / 50 °C 5.1: tetrahydrofuran / 20 - 35 °C 6.1: 91 percent / CuCl; iPr2NEt; Celite / toluene; acetonitrile / 0.5 h / 80 °C 7.1: LHMDS / tetrahydrofuran / -10 °C 8.1: TMSCl; NaI / H2O; CH2Cl2 / 0.33 h / 20 - 25 °C View Scheme
参考文献
Wang, Xiao-Jun; Zhang, Li; Xu, Yibo; Krishnamurthy, Dhileepkumar; Varsolona, Richard; Nummy, Laurence; Shen, Sherry; Frutos, Rogelio P.; Byrne, Denis; Chung; Farina, Vittorio; Senanayake, Chris H.
Tetrahedron Letters, 2005 , vol. 46, # 2 p. 273 - 276
