二乙基2-[[(3-氯苯基)氨基]亚甲基]丙二酸酯合成路线 （共 19 条）
反应条件
2: aqueous NaOH 3: 250 - 270 °C / oder in einem Gemisch von Diphenylaether und Biphenyl 4: phosphoryl chloride View Scheme
参考文献
De; Byers; Krogstad
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 315 - 320
反应条件
1: diphenyl ether / 1 h / Heating 2: 2 N aq. NaOH / 1 h / Heating 3: diphenyl ether / 1 h / Heating 4: POCl3 / 100 °C 5: 90 percent / 1.) 80 deg C, 1 h, 2.) 135-145 deg C, 3 h View Scheme
参考文献
De; Byers; Krogstad
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 315 - 320
反应条件
1: in diphenylether T=250°C; 1 h; 2: With thionyl chloride T=80°C; 1 h;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6351 - 6363
反应条件
1: various solvent(s) / 0.5 h / 250 °C 2: POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
参考文献
Karolak-Wojciechowska, Janina; Lange, Jerzy; Ksiazek, Waldemar; Gniewosz, Malgorzata; Rump, Slawomir
Farmaco, 1998 , vol. 53, # 8-9 p. 579 - 585
参考文献
Price; Roberts
Journal of the American Chemical Society, 1946 , vol. 68, p. 1204,1206
Organic Syntheses, 1955 , vol. Coll. Vol. III, p. 272
反应条件
sulfuric acid; acetic anhydride
参考文献
Agui; Komatsu; Nakagome
Journal of Heterocyclic Chemistry, 1975 , vol. 12, # 3 p. 557 - 563
反应条件
1: diphenyl ether / 1 h / Heating 2: 2 N aq. NaOH / 1 h / Heating 3: diphenyl ether / 1 h / Heating 4: POCl3 / 100 °C 5: 1.) 100 deg C, 2 h, 2.) 150-160 deg C, 5 h View Scheme
参考文献
De; Byers; Krogstad
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 315 - 320
反应条件
sulfuric acid; acetic anhydride
参考文献
Agui; Komatsu; Nakagome
Journal of Heterocyclic Chemistry, 1975 , vol. 12, # 3 p. 557 - 563
