6-氯-3-甲氧基吡嗪-4-羧酰胺合成路线 （共 2 条）
反应条件
1: in methanol T=20°C; 3.25 h; 2: With ammonia in water T=0°C; 24 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/108707 A1, 2004 ;
Location in patent: Page 54 ;
WO 2004/108707 A1
反应条件
sodium hydroxide; bromine in water T=0 - 70°C; 4 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/108707 A1, 2004 ;
Location in patent: Page 55-56 ;
WO 2004/108707 A1
