oxygen; dimethyl amine; copper dichloride 20 h;

1: With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; enolization; 0.5 h; 2: With (+)-(2S,8aS)-(camphorylsulfonyl)oxaziridine in tetrahydrofuran T=-78°C; Substitution; asymmetric hydroxylation; 3 h;