5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-羧酸合成路线 （共 5 条）
反应条件
acetic acid 5 h; Heating;
参考文献
Timoshchuk, V. A.
Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 7 p. 1198 - 1204
Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 7 p. 1512 - 1519
反应条件
1: 45 percent / triethylamine, diphenylphosphoryl azide / dimethylformamide / 1.) -20 deg C, 1 h, 2.) 20 deg C, 20 h
2: NaNO2, formic acid / 0.5 h
View Scheme
参考文献
Montgomery, John A.; Thomas, H. Jeanette; Brockman, R. Wallace; Wheeler, Glynn P.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 184 - 189
反应条件
1: 53 percent / triethylamine, diphenylphosphoryl azide / dimethylformamide / 1.) -20 deg C, 1 h, 2.) 20 deg C, 20 h
2: 38 percent / NaNO2, formic acid / 0.5 h
View Scheme
参考文献
Montgomery, John A.; Thomas, H. Jeanette; Brockman, R. Wallace; Wheeler, Glynn P.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 184 - 189
反应条件
diphenylphosphoranyl azide; triethylamine in N,N-dimethyl-formamide
1.) -20 deg C, 1 h, 2.) 20 deg C, 20 h;
参考文献
Montgomery, John A.; Thomas, H. Jeanette; Brockman, R. Wallace; Wheeler, Glynn P.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 184 - 189
反应条件
diphenylphosphoranyl azide; triethylamine in N,N-dimethyl-formamide
1.) -20 deg C, 1 h, 2.) 20 deg C, 20 h;
参考文献
Montgomery, John A.; Thomas, H. Jeanette; Brockman, R. Wallace; Wheeler, Glynn P.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 184 - 189
