N-甲基-N-苯基萘-1-胺合成路线 （共 7 条）
反应条件
potassium tert-butylate; N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene-acetylacetonate palladium chloride in ethylene glycol dimethyl ether T=50°C; Buchwald-Hartwig amination; 3 h;
参考文献
PROMERUS LLC
Patent: WO2006/128097 A1, 2006 ;
Location in patent: Page/Page column 17, 32, 38 ;
反应条件
potassium fluoride; 18-crown-6 ether; ammonium hydrogen carbonate in tetrahydrofuran T=60°C; 12 h; Inert atmosphere;
参考文献
Bhojgude, Sachin Suresh; Kaicharla, Trinadh; Biju, Akkattu T.
Organic Letters, 2013 , vol. 15, # 21 p. 5452 - 5455
反应条件
cerium monofluoride in toluene; acetonitrile Inert atmosphereReflux;
参考文献
Cant, Alastair A.; Bertrand, Guillaume H. V.; Henderson, Jaclyn L.; Roberts, Lee; Greaney, Michael F.
Angewandte Chemie - International Edition, 2009 , vol. 48, # 28 p. 5199 - 5202
反应条件
caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; bis (triortho-tolylphosphine)palladium(II) chloride T=120°C; 2 h;
参考文献
Romero; Harrak; Basset; Ginet; Constans; Pujol
Tetrahedron, 2006 , vol. 62, # 38 p. 9010 - 9016
反应条件
[(tris(1-pyrazolyl)borate)Ru(P(phenyl)3)(CH3CN)2]PF6 T=100°C; 15 h;
参考文献
Odedra, Arjan; Wu, Chang-Jung; Pratap, Taduri Bhanu; Huang, Chun-Wei; Ran, Ying-Fen; Liu, Rai-Shung
Journal of the American Chemical Society, 2005 , vol. 127, # 10 p. 3406 - 3412
反应条件
potassium hydroxide 1.) 100 deg C, 1 h, 2.) reflux, 2 h; Yield given. Multistep reaction;
参考文献
Grellmann, K. H.; Schmitt, U.
Journal of the American Chemical Society, 1982 , vol. 104, # 23 p. 6267 - 6272
反应条件
phenyllithium 1.) cyclohexane, ether, -30 deg C, 2.) cyclohexane, ether, RT, overnight; Yield given. Multistep reaction;
参考文献
Casarini, D.; Lunazzi, L.
Journal of Organic Chemistry, 1988 , vol. 53, # 1 p. 182 - 185
