5,6,7,8-四氢-咪唑[1,2-A]吡啶合成路线 (共 6 条)
反应条件
tin(IV) chloride in dichloromethane; 1,3,5-trimethyl-benzene 51 h; Heating;
参考文献
Hua, Duy H.; Zhang, Fengqi; Chen, Jinshan; Robinson, Paul D.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 5084 - 5087
反应条件
sodium iodide in methanol Finkelstein cyclization; 6 h; Heating;
参考文献
Kan, Huang-Chuan; Tseng, Ming-Chung; Chu, Yen-Ho
Tetrahedron, 2007 , vol. 63, # 7 p. 1644 - 1653
反应条件
sodium iodide; methyloxirane in 1,4-dioxane; methanol; dichloromethane; butanone
参考文献
US5039691 A1, ;
US 5039691 A
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 5 h; Heating;
参考文献
Aldabbagh, Fawaz; Bowman, W. Russell
Tetrahedron, 1999 , vol. 55, # 13 p. 4109 - 4122
反应条件
1: 74 percent / hydrogen chloride / diethyl ether / 4 h / 20 °C 2: triethylamine / CH2Cl2 / 2 h / 60 °C 3: formic acid / 20 h / 80 °C 4: 97 percent / sodium iodide / methanol / 6 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 63, # 7 p. 1644 - 1653
反应条件
1: triethylamine / CH2Cl2 / 2 h / 60 °C 2: formic acid / 20 h / 80 °C 3: 97 percent / sodium iodide / methanol / 6 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 63, # 7 p. 1644 - 1653