5 Pd(II)/C(eggshell); hydrogen

trichlorophosphate 3 h; Heating; Title compound not separated from byproducts;

1: 5 Pd(II)/C(eggshell); hydrogen 2: acetonitrile / 12 h / Reflux 3: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 8 h / 20 °C / 7500.75 Torr View Scheme

trichlorophosphate 3 h; Heating; Title compound not separated from byproducts;

1: 5 Pd(II)/C(eggshell); hydrogen 2: acetonitrile / 12 h / Reflux 3: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 8 h / 20 °C / 7500.75 Torr 4: (R)-(-)-α-hydroxybenzeneacetic acid / ethyl acetate / 4 h / Reflux; Resolution of racemate View Scheme

1: 5 Pd(II)/C(eggshell); hydrogen 2: acetonitrile / 12 h / Reflux 3: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 8 h / 20 °C / 7500.75 Torr 4: (S)-α-hydroxybenzeneacetic acid / ethyl acetate / 4 h / Reflux; Resolution of racemate 5: hydrogenchloride / diethyl ether / 2 h / 0 °C View Scheme

1: 5 Pd(II)/C(eggshell); hydrogen 2: acetonitrile / 12 h / Reflux 3: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 8 h / 20 °C / 7500.75 Torr View Scheme

1.1: 144 h / 20 °C / Inert atmosphere 2.1: ethanol; water / 0.83 h / 50 °C 2.2: Cooling with ice 3.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C 4.1: hydrogenchloride / water / 100 °C 5.1: tetrahydrofuran / Reflux 6.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 7.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 7.2: pH 7 View Scheme