n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.166667 h;

1: 83 percent / n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C 2: AlCl3 / CH2Cl2 / 2 h / 20 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; cyclohexane / 0.25 h / -78 °C 1.2: -78 - 20 °C 2.1: n-butyllithium / tetrahydrofuran; cyclohexane / 0.33 h / -78 °C 2.2: -78 - 20 °C 3.1: bromine / dichloromethane / 0 - 20 °C View Scheme