N-[4-氯-3-(三异丙基硅烷基氧基)苯基]-2,2-二甲基丙酰胺合成路线 （共 4 条）
反应条件
1: BBr3 / CH2Cl2 2: imidazole / dimethylformamide 3: H2 / Pd/C / ethyl acetate 4: Et3N / CH2Cl2 View Scheme
参考文献
Markwalder, Jay A.; Christ, David D.; Mutlib, Abdul; Cordova, Beverly C.; Klabe, Ronald M.; Seitz, Steven P.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 619 - 622
反应条件
1: imidazole / dimethylformamide 2: H2 / Pd/C / ethyl acetate 3: Et3N / CH2Cl2 View Scheme
参考文献
Markwalder, Jay A.; Christ, David D.; Mutlib, Abdul; Cordova, Beverly C.; Klabe, Ronald M.; Seitz, Steven P.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 619 - 622
反应条件
triethylamine in dichloromethane
参考文献
Markwalder, Jay A.; Christ, David D.; Mutlib, Abdul; Cordova, Beverly C.; Klabe, Ronald M.; Seitz, Steven P.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 619 - 622
反应条件
1: s-BuLi / diethyl ether / 0 - 20 °C 2: aq. HCl / 1,2-dimethoxy-ethane 3: imidazole / dimethylformamide View Scheme
参考文献
Markwalder, Jay A.; Christ, David D.; Mutlib, Abdul; Cordova, Beverly C.; Klabe, Ronald M.; Seitz, Steven P.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 619 - 622
