N-(2-二乙胺基乙基)-5-(5-氟-2-氧代-1,2-二氢吲哚-3-基亚甲基)-2,4-二甲基-1H-吡咯-3-甲酰胺合成路线 （共 2 条）
反应条件
pyrrolidine in ethanol 5 h; Reflux;
参考文献
WO2010/49449 A2, ;
Page/Page column 16; 17 ;
反应条件
1: N,N-dimethyl-formamide; N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide With phosgene in acetonitrile T=20°C; 2: 5-Fluoro-1,3-dihydro-2H-indol-2-one With potassium hydroxide in acetonitrile T=20°C; Product distribution / selectivity;
参考文献
RATIOPHARM GMBH; CHRIST, Jochen; STRIEGEL, Hans-Guenter
Patent: WO2010/136458 A1, 2010 ;
Location in patent: Page/Page column 27; 28 ;
