1.1: 80 percent / Pd(OAc)2; PPh3; Et3N / dimethylformamide / 20 h / 20 °C 2.1: 2,6-lutidine; LiCl / dimethylformamide / 0.5 h / 0 °C 2.2: 77 percent / methanesulfonyl chloride / dimethylformamide / 2 h / 0 °C 3.1: n-BuLi / hexane; tetrahydrofuran / 0.25 h / -50 °C 4.1: 3.00 g / aq. H2O2 / CHCl3 / 0.02 h View Scheme