4-N-甲基苄基-n-乙氧甲酰哌啶双盐酸盐合成路线 （共 14 条）
反应条件
1: With trifluorormethanesulfonic acid T=20°C; 4 h; 2: With sodium hydroxide in water T=0°C;
参考文献
Egle, Ian; Isaac, Methvin; Urbanek, Rebecca; McLaren, Frances M.; Walsh, Sally B.; Steelman, Gary B.; Brown, Dean G.; Nugiel, David; Chen, Deborah W.; Slassi, Abdelmalik; Ma, Fupeng
Patent: US2009/192169 A1, 2009 ;
Location in patent: Page/Page column 66 ;
反应条件
hydrogen; Pd-BaSO4 T=80°C; P=3750.3 Torr; 7 h;
参考文献
Schaefer; Hackmack; Eistetter; Krueger; Menge; Klosa
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 3 p. 233 - 240
反应条件
trifluorormethanesulfonic acid T=20°C; Substitution; 3 h;
参考文献
Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705
反应条件
trifluorormethanesulfonic acid T=20°C; Substitution;
参考文献
Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705
反应条件
hydrogen bromide 2 h; Heating;
参考文献
Schaefer; Hackmack; Eistetter; Krueger; Menge; Klosa
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 3 p. 233 - 240
反应条件
1: AlCl3 / 2 h / 60 °C 2: 80 percent / H2 / 5percent Pd/BaSO4 / 7 h / 80 °C / 3750.3 Torr View Scheme
参考文献
Schaefer; Hackmack; Eistetter; Krueger; Menge; Klosa
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 3 p. 233 - 240
反应条件
aluminium trichloride T=60°C; 1 h;
参考文献
Schaefer; Hackmack; Eistetter; Krueger; Menge; Klosa
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 3 p. 233 - 240
反应条件
trifluorormethanesulfonic acid T=20°C; Substitution;
参考文献
Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705
反应条件
trifluorormethanesulfonic acid T=20°C; Substitution;
参考文献
Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705
反应条件
1: AlCl3 / 2 h / 60 °C 2: 80 percent / H2 / 5percent Pd/BaSO4 / 7 h / 80 °C / 3750.3 Torr View Scheme
参考文献
Schaefer; Hackmack; Eistetter; Krueger; Menge; Klosa
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 3 p. 233 - 240
