(S,S)-(+)-1-苯基环己烷-顺-1,2-二醇合成路线 (共 9 条)
反应条件
N-methyl-2-indolinone; fluorous OsO4 in water; tert-butyl alcohol T=60°C; 36 h;
参考文献
Huang, Yangen; Meng, Wei-Dong; Qing, Feng-Ling
Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1965 - 1968
反应条件
1: in tetrahydrofuran T=-78 - 20°C; Inert atmosphere; 2: With hydrogenchloride; ammonium chloride in tetrahydrofuran; water Inert atmosphere; diastereoselective reaction;
参考文献
Angewandte Chemie, International Edition, , vol. 48, p. 3333 - 3336
Angewandte Chemie, , vol. 121, p. 3383 - 3386
反应条件
sulfuric acid in 1,4-dioxane; water T=25°C; 0.0333333 h; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 109, # 5 p. 1463 - 1469
反应条件
potassium hydroxide in 1,4-dioxane
参考文献
Tetrahedron, , vol. 21, p. 3277 - 3283
反应条件
methanol; sodium carbonate 12 h;
参考文献
Organic Letters, , vol. 12, # 11 p. 2450 - 2452
反应条件
acetic acid buffer; sodium perchlorate in 1,4-dioxane; water T=25°C; Hydrolysis; pH=4.0; KineticsProduct distribution;
参考文献
Journal of Organic Chemistry, , vol. 64, # 17 p. 6227 - 6234
反应条件
ruthenium trichloride; Oxonereg;; sodium hydrogencarbonate in water; acetonitrile T=20°C; 4.8 h; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 66, # 14 p. 4814 - 4818
反应条件
(i) aq. H2O2, HCO2H, K2CO3, Et2O, (ii) aq. KOH, MeOH; Multistep reaction;
参考文献
Tetrahedron, , vol. 21, p. 3277 - 3283
反应条件
nickel in ethanol 2 h; Heating;
参考文献
King, S. Bruce; Sharpless, K. Barry
Tetrahedron Letters, 1994 , vol. 35, # 31 p. 5611 - 5612