(1S,2R)-(+)-反-2-苯基-1-环己醇合成路线 （共 48 条）
反应条件
1: 77 percent / pyridine 2: H2 / Raney nickel / methanol / 72 h / 20 °C / 8274.59 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 12 p. 4276 - 4284
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 52, # 2 p. 310 - 311
反应条件
1: paraformaldehyde; 3 Angstroem molecular sieves / toluene / Heating 2: H2 / 10 percent Pd/C / methanol / 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 25 p. 8447 - 8453
反应条件
(S)-HBTM; N-ethyl-N,N-diisopropylamine in chloroform-d1 T=20°C; 3 h; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 10, # 6 p. 1115 - 1118
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C; 24 h;
参考文献
Synthetic Communications, , vol. 43, # 10 p. 1425 - 1431
反应条件
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 37, # 47 p. 8543 - 8546
反应条件
1: trimethylsilyl bromide; triethylamine / acetonitrile / 18 h / -25 °C / |Inert atmosphere 2: silver nitrate / acetone; water / 3 h / |Reflux 3: acetic acid; zinc / 24 h 4: sodium cyanoborohydride / 1 h 5: hydrogen / methanol / 3.5 h / 20 °C / 18751.9 Torr / |Autoclave 6: dichloromethane / 2 h / 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 46 p. 8082 - 8091
反应条件
1: silver nitrate / acetone; water / 3 h / |Reflux 2: acetic acid; zinc / 24 h 3: sodium cyanoborohydride / 1 h 4: hydrogen / methanol / 3.5 h / 20 °C / 18751.9 Torr / |Autoclave 5: dichloromethane / 2 h / 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 46 p. 8082 - 8091
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / |Reflux 2: ammonium acetate / |Heating 3: tin(IV) chloride / dichloromethane / -94 °C 4: trimethylsilyl bromide; triethylamine / acetonitrile / 18 h / -25 °C / |Inert atmosphere 5: silver nitrate / acetone; water / 3 h / |Reflux 6: acetic acid; zinc / 24 h 7: sodium cyanoborohydride / 1 h 8: hydrogen / methanol / 3.5 h / 20 °C / 18751.9 Torr / |Autoclave 9: dichloromethane / 2 h / 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 46 p. 8082 - 8091
反应条件
1: ammonium acetate / |Heating 2: tin(IV) chloride / dichloromethane / -94 °C 3: trimethylsilyl bromide; triethylamine / acetonitrile / 18 h / -25 °C / |Inert atmosphere 4: silver nitrate / acetone; water / 3 h / |Reflux 5: acetic acid; zinc / 24 h 6: sodium cyanoborohydride / 1 h 7: hydrogen / methanol / 3.5 h / 20 °C / 18751.9 Torr / |Autoclave 8: dichloromethane / 2 h / 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 46 p. 8082 - 8091
