(1S,2R)-(+)-反-2-苯基-1-环己醇合成路线 (共 48 条)
反应条件
IpcBH2 Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 45, # 17 p. 3543 - 3544
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 12 h; RefluxInert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 352, # 5 p. 855 - 868
反应条件
in various solvent(s) 96 h; Ambient temperaturePseudomonas sp. lipase;
参考文献
Journal of the Chemical Society, Chemical Communications, , # l p. 49 - 51
反应条件
BF3*Bu2O; (1R,2R)-1,2-diphenyl-1,2-dimethoxyethane in diethyl ether; cyclohexane T=-78°C; 0.583333 h; enantioselective opening of oxirane, other educts, other reagents, solvent effect; Product distribution;
参考文献
Tetrahedron, , vol. 53, # 31 p. 10699 - 10708
反应条件
n-butyllithium; boron trifluoride diethyl etherate; (-)-sparteine in diethyl ether; hexane T=-78°C; Product distribution; Further Variations:Reagents;
参考文献
Tetrahedron, , vol. 60, # 42 p. 9479 - 9484
反应条件
MS 4 Angstroem; (S)-1-methyl-2-[(dihydroisoindol-2-yl)methyl]pyrrolidine; tin(ll) chloride in dichloromethane 24 h; Ambient temperaturereactions under var. conditions and reactions of derivatives; Product distribution;
参考文献
Tetrahedron Letters, , vol. 37, # 47 p. 8543 - 8546
反应条件
sodium hypochlorite; 3-methyl-4-oxa-5-azahomoadamantane; sodium hydrogencarbonate; potassium bromide in dichloromethane; water T=0°C; 0.333333 h; Inert atmosphere;
参考文献
Sasano, Yusuke; Murakami, Keiichi; Nishiyama, Tomohiro; Kwon, Eunsang; Iwabuchi, Yoshiharu
Angewandte Chemie - International Edition, 2013 , vol. 52, # 48 p. 12624 - 12627
Angew. Chem., 2013 , vol. 125, # 48 p. 12856 - 12859,4
反应条件
1: pyridine; chromium(VI) oxide in dichloromethane T=20°C; Inert atmosphere; 2: (1S,2R)-(+)-1-hydroxy-2-phenylcyclohexane in dichloromethane T=20°C; 0.25 h; Inert atmosphere;
参考文献
Balamurugan, Rengarajan; Gudla, Vanajakshi
Organic Letters, 2009 , vol. 11, # 14 p. 3116 - 3119