1: With trifluoroacetic acid 6 h; Heating / reflux; 2: With sodium tetrahydroborate in ethanol T=20°C; 60 h;

pyridine; copper diacetate in 1,4-dioxane Chan-Lam reaction; 2 h; Reflux;

1: 3-amino-quinoline With potassium hydride in tetrahydrofuran; hexane T=0°C; 0.5 h; Inert atmosphere; 2: methyl iodide in tetrahydrofuran; hexane T=0 - 20°C; 10 h; Inert atmosphere;