(S)-3-羟基-2-吡咯烷酮合成路线 (共 6 条)
反应条件
1: With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane in anhydrous xylene 16 h; Reflux; 2: With hydrogenchloride in water
参考文献
Davies, Christopher D.; Elliott, Mark C.; Hill-Cousins, Joseph; Khan, Misbah-Ul A.; Maqbool, Tahir; Wood, John L.
Synlett, 2008 , # 13 p. 2028 - 2032
反应条件
1: With triphenylphosphine in tetrahydrofuran T=20°C; 6 h; 2: With water in tetrahydrofuran T=20°C; 48 h;
参考文献
Huang, Pei-Qiang; Zheng, Xiao; Wei, Hua
Heterocycles, 2003 , vol. 60, # 8 p. 1833 - 1841
反应条件
hydrogen; palladium on activated charcoal in isopropyl alcohol 12 h;
参考文献
Pires, Raul; Burger, Klaus
Tetrahedron, 1997 , vol. 53, # 27 p. 9213 - 9218
反应条件
hydrogen; palladium on activated charcoal in isopropyl alcohol 12 h;
参考文献
Pires, Raul; Burger, Klaus
Tetrahedron, 1997 , vol. 53, # 27 p. 9213 - 9218
反应条件
hydrogenchloride in isopropyl alcohol Product distribution;
参考文献
Bulletin de la Societe Chimique de France, , # 2 p. 297 - 301
反应条件
1: With di-isopropyl azodicarboxylate; triphenylphosphine; 4-nitro-benzoic acid in tetrahydrofuran T=20°C; 2: With potassium carbonate in methanol T=20°C;
参考文献
CADILA HEALTHCARE LIMITED; KHARUL, Rajendra; JAIN, Mukul, R.; PATEL, Pankaj, R.
Patent: WO2011/13141 A2, 2011 ;
Location in patent: Page/Page column 50 ;
WO 2011/013141 A2