2-氯-6-甲氧基吡啶-3-胺合成路线 (共 2 条)
反应条件
hydrogen in tetrahydrofuran T=37°C; P=2250.23 Torr; 12 h; chemoselective reaction;
参考文献
Kasparian, Annie J.; Savarin, Cecile; Allgeier, Alan M.; Walker, Shawn D.
Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9841 - 9844
反应条件
1: With hydrogenchloride; sodium nitrite in water
T=-5°C; 0.333333 h;
2: With copper(l) chloride in water
T=-5 - 20°C; 3.41667 h;
3: With sodium hydroxide in water
pH=10 - 11;
参考文献
N.V. Organon
Patent: US2007/112019 A1, 2007 ;
Location in patent: Page/Page column 13/2 ;