potassium hydroxide in water

1: alkali metal carbonate / N,N-dimethyl-formamide / 3 h / 50 °C 2: sodium nitrite; acetic acid / 16 h / 20 °C 3: sodium hydroxide; water / 1 h / 50 °C View Scheme

1: sodium nitrite; acetic acid / 16 h / 20 °C 2: sodium hydroxide; water / 1 h / 50 °C View Scheme

1: N-<3-(dimethylamino)propyl>-N'-ethylcarbodiimide hydrochloride / various solvent(s) / 25 °C / half-life value of the ring transformation, other 6-oxo-purines 2: 77 percent / conc. aq. ammonia / 2 h / Ambient temperature View Scheme