2-甲基-4,4,4-三氟乙酰乙酸乙酯合成路线 (共 8 条)
反应条件
sodium hydride; potassium iodide in acetone 72 h; Heating;
参考文献
Aubert, Corinne; Begue, Jean-Pierre; Charpentier-Morize, Micheline; Nee, Gerard; Langlois, Bernard
Journal of Fluorine Chemistry, 1989 , vol. 44, p. 361 - 376
反应条件
diethyl ether; sodium ethanolate anschliessendes 12-taegiges Behandeln mit Aethylpropionat;
参考文献
Journal of the American Chemical Society, , vol. 78, p. 4053,4056
反应条件
sodium in diethyl ether
参考文献
Tetrahedron, , vol. 20, p. 2162 - 2166
反应条件
sodium hydride in toluene
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 12 p. 3505 - 3510
反应条件
sulfuric acid; acetic acid
参考文献
Burdon,J.; McLoughlin,V.C.R.
Tetrahedron, 1964 , vol. 20, p. 2162 - 2166
反应条件
nitrogen; hydrogen; triethylamine; Pt/C
参考文献
Chong, Joshua Anthony; Abdesaken, Fereydon; Spangler, Lori Ann; Roemmele, Renee Caroline; Stephens, Randall Wayne; Nightingale, Peter David; Hartley, David John
Patent: US6307094 B1, 2001 ;
反应条件
sodium borohydride; ammonium chloride in ethanol; dichloromethane; water; acetone
参考文献
Merrell Pharmaceuticals Inc.
Patent: US5496927 A1, 1996 ;
反应条件
hydrazine in ethylene glycol dimethyl ether; toluene
参考文献
American Home Products Corporation
Patent: US5274111 A1, 1993 ;