4-甲基吡咯-2-羧酸甲酯合成路线 （共 24 条）
反应条件
1: TBAF / tetrahydrofuran / 8 h / 60 °C 2: Cu(OAc)2; i-Pr2NEt / methoxybenzene / 12 h / 130 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 15 p. 2563 - 2566
反应条件
1: Br2, NaOH 2: H2SO4 3: 94 percent / Li / methanol / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 10 p. 1523 - 1526
反应条件
triethylamine in acetonitrile RefluxInert atmosphere;
参考文献
Tetrahedron Letters, , vol. 51, # 31 p. 4150 - 4152
反应条件
1: hydrogen chloride 2: 21 g / potassium hydroxide 3: 27 g / aq. hydrochloric acid, acetic acid 4: 83 percent / sodium methoxide / methanol View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 1459 - 1462
反应条件
1: 21 g / potassium hydroxide 2: 27 g / aq. hydrochloric acid, acetic acid 3: 83 percent / sodium methoxide / methanol View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 1459 - 1462
反应条件
1: 27 g / aq. hydrochloric acid, acetic acid 2: 83 percent / sodium methoxide / methanol View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 1459 - 1462
反应条件
pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate 1) r.t. 2) THF, reflux; Yield given. Multistep reaction;
参考文献
Journal of Heterocyclic Chemistry, , vol. 28, # 7 p. 1671 - 1676
反应条件
hydrogenchloride 1) reflux, 5 h, methanol; Multistep reaction;
参考文献
Tetrahedron, , vol. 55, # 13 p. 4133 - 4152
反应条件
hexacarbonyl molybdenum; silica gel; triethylamine; trifluoroacetic acid 1.) acetonitrile, reflux, 1 at, 4 h 2.) rt, 1 h; Yield given. Multistep reaction;
参考文献
Liebigs Annalen der Chemie, , # 7 p. 709 - 714
反应条件
1: aqueous KOH 2: methanol; diethyl ether View Scheme
参考文献
Annali di Chimica (Rome, Italy), , vol. 46, p. 847,854
