2-(3-甲基苯基)-1-苯乙酮合成路线 （共 7 条）
反应条件
in tetrahydrofuran T=-78°C; 3 h; Inert atmosphere;
参考文献
N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian
Patent: WO2011/38204 A1, 2011 ;
Location in patent: Page/Page column 137 ;
WO 2011/038204 A1
反应条件
1,4-diaza-bicyclo[2.2.2]octane; water; oxygen in acetonitrile T=80°C; P=760.051 Torr; 12 h; chemoselective reaction;
参考文献
Su, Yijin; Sun, Xiang; Wu, Guolin; Jiao, Ning
Angewandte Chemie - International Edition, 2013 , vol. 52, # 37 p. 9808 - 9812
Angew. Chem., 2013 , p. 9990 - 9994
反应条件
hydrogenchloride; iodine; magnesium in water; benzonitrile
参考文献
Dainippon Pharmaceutical Co., Ltd.
Patent: US4080453 A1, 1978 ;
反应条件
water; palladium diacetate; potassium hydrogencarbonate; tri-cyclo-hexyl-phosphine T=100°C; Suzuki coupling; P=7500.75 Torr; 20 h; Inert atmosphere;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 5 p. 788 - 792
反应条件
1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 20 °C 2: tetrahydrofuran / 3 h / -78 °C / Inert atmosphere View Scheme
参考文献
N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian
Patent: WO2011/38204 A1, 2011 ;
WO 2011/038204 A1
反应条件
potassium tert-butylate Yield given. Multistep reaction;
参考文献
Dell'Erba; Novi; Petrillo; Tavani
Tetrahedron, 1993 , vol. 49, # 1 p. 235 - 242
反应条件
thiophenol in benzene Irradiation; Product distributionQuantum yieldKinetics;
参考文献
Netto-Ferreira, J.C.; Avellar, I.G.J.; Scaiano, J.C.
Journal of Organic Chemistry, 1990 , vol. 55, # 1 p. 89 - 92
