1.1: BuLi / hexane; tetrahydrofuran / 0.33 h / -78 °C 1.2: 67.9 percent / hexane; tetrahydrofuran / 7 h / -78 - 20 °C 2.1: 96.6 percent / Bu3NF*H2O / tetrahydrofuran / 0.67 h / 0 °C 3.1: 96.8 percent / MsCl; 2,6-dimethylpyridine; LiCl / dimethylformamide / 4 h / -5 °C 4.1: BuLi / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / 0.5 h / -70 °C 4.2: 75.8 percent / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / 3 h / -70 - 20 °C 5.1: EtNH2; Li / tetrahydrofuran / 0.5 h / -78 °C 5.2: 86.1 percent / isoprene; NH4Cl / tetrahydrofuran 6.1: 93 percent / aq. HCl / methanol; hexane / 4 h / 40 °C View Scheme

(i) Ni(CO)4, (ii) /BRN= 2594367/, (iii) aq. FeCl3; Multistep reaction;