4-羟基-1,4-二(苯基)丁-3-烯-2-酮合成路线 （共 25 条）
参考文献
Smith; Kelly
Journal of the American Chemical Society, 1952 , vol. 74, p. 3305,3308
反应条件
Claisen condensation;
参考文献
Claramunt, Rosa M.; Cornago, Pilar; Torres, Veronica; Pinilla, Elena; Torres, M. Rosario; Samat, Andre; Lokshin, Vladimir; Vales, Magali; Elguero, Jose
Journal of Organic Chemistry, 2006 , vol. 71, # 18 p. 6881 - 6891
反应条件
1: SnCl4 / 1 h / -78 °C 2: mCPBA / CH2Cl2 / 0.5 h / -50 °C 3: NaHCO3 / 1,3,5-trimethyl-benzene / Heating 4: 59 percent / ZnCl2 / trifluoroacetic acid; H2O / 1 h / Ambient temperature View Scheme
参考文献
Sato, Tsuneo; Inoue, Masami; Kobara, Satoru; Otera, Junzo; Nozaki, Hitosi
Tetrahedron Letters, 1989 , vol. 30, # 1 p. 91 - 94
反应条件
1: mCPBA / CH2Cl2 / 0.5 h / -50 °C 2: NaHCO3 / 1,3,5-trimethyl-benzene / Heating 3: 59 percent / ZnCl2 / trifluoroacetic acid; H2O / 1 h / Ambient temperature View Scheme
参考文献
Sato, Tsuneo; Inoue, Masami; Kobara, Satoru; Otera, Junzo; Nozaki, Hitosi
Tetrahedron Letters, 1989 , vol. 30, # 1 p. 91 - 94
反应条件
1: 1) BuLi / CH2Cl2 / 1) -78 to 0 deg C, 0.5 h, 2) 0 deg C., 1 h 2: SnCl4 / 1 h / -78 °C 3: mCPBA / CH2Cl2 / 0.5 h / -50 °C 4: NaHCO3 / 1,3,5-trimethyl-benzene / Heating 5: 59 percent / ZnCl2 / trifluoroacetic acid; H2O / 1 h / Ambient temperature View Scheme
参考文献
Sato, Tsuneo; Inoue, Masami; Kobara, Satoru; Otera, Junzo; Nozaki, Hitosi
Tetrahedron Letters, 1989 , vol. 30, # 1 p. 91 - 94
反应条件
1: SnCl4 / 1 h / -78 °C 2: mCPBA / CH2Cl2 / 0.5 h / -50 °C 3: NaHCO3 / 1,3,5-trimethyl-benzene / Heating 4: 59 percent / ZnCl2 / trifluoroacetic acid; H2O / 1 h / Ambient temperature View Scheme
参考文献
Sato, Tsuneo; Inoue, Masami; Kobara, Satoru; Otera, Junzo; Nozaki, Hitosi
Tetrahedron Letters, 1989 , vol. 30, # 1 p. 91 - 94
反应条件
Claisen condensation;
参考文献
Yamada, Tohru; Nagata, Takushi; Sugi, Kiyoaki D.; Yorozu, Kiyotaka; Ikeno, Taketo; Ohtsuka, Yuhki; Miyazaki, Daichi; Mukaiyama, Teruaki
Chemistry - A European Journal, 2003 , vol. 9, # 18 p. 4485 - 4509
参考文献
McElvain; Weber
Journal of the American Chemical Society, 1941 , vol. 63, p. 2192,2193
反应条件
nachfolgend Zers. mit Salzsaeure;
参考文献
Kohler, Engelbrecht
Journal of the American Chemical Society, 1919 , vol. 41, p. 1383
反应条件
hydroxylamine hydrochloride
参考文献
Buelow; Grotowsky
Chemische Berichte, 1901 , vol. 34, p. 1485
