4-(甲基巯基)苯甲醛合成路线 （共 113 条）
参考文献
Singh, Palwinder; Mittal, Anu; Kaur, Satwinderjeet; Holzer, Wolfgang; Kumar, Subodh
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 15 p. 2706 - 2712
反应条件
sodium cyanide in ethanol; water
Reflux;
参考文献
Singh, Palwinder; Mittal, Anu; Kaur, Satwinderjeet; Holzer, Wolfgang; Kumar, Subodh
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 15 p. 2706 - 2712
反应条件
1: 1.) LiOEt, 2.) OxoneTM / 1.) EtOH, RT, 2.5 h, 2.) aq. MeOH, a) 0 deg C, 15 min, b) RT, 1.5 h
2: 72 percent / KMnO4, Ac2O / 0 °C
View Scheme
参考文献
Barta, Thomas E.; Stealey, Michael A.; Collins, Paul W.; Weier, Richard M.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 24 p. 3443 - 3448
反应条件
in tetrahydrofuran
T=20°C; 12 h;
参考文献
Zhang, Wei; Benmohamed, Radhia; Arvanites, Anthony C.; Morimoto, Richard I.; Ferrante, Robert J.; Kirsch, Donald R.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 1029 - 1045
反应条件
sodium hydroxide
3 h; Ambient temperature;
参考文献
Rehse; Ruther
Archiv der Pharmazie, 1984 , vol. 317, # 2 p. 163 - 167
反应条件
1: 16.85 g / piperidine; pyridine / 3 h / Heating
2: 100 mg / H2 / Pd/C / ethyl acetate; ethanol / 168 h / 20 °C
3: 4.25 g / aq. H2SO4 / CH2Cl2 / Heating
4: 2.72 g / LiAlH4 / diethyl ether
View Scheme
参考文献
Tachikawa, Takashi; Yoshida, Akihiro; Tojo, Sachiko; Sugimoto, Akira; Fujitsuka, Mamoru; Majima, Tetsuro
Chemistry - A European Journal, 2004 , vol. 10, # 21 p. 5345 - 5353
反应条件
nitric acid; phosphorus pentoxide; silica gel in water
0.0833333 h;
参考文献
Hajipour, Abdol R.; Guo, Lian-Wang; Ruoho, Arnold E.
Molecular Crystals and Liquid Crystals, 2006 , vol. 456, # 1 p. 85 - 93
反应条件
sodium dithionite in formic acid; toluene
参考文献
Societe Anonyme dite: L'Oreal
Patent: US4980509 A1, 1990 ;
反应条件
dihydrogen peroxide
T=50°C; 4 h;
参考文献
Yamada, Yoichi M. A.; Tabata, Hidetsugu; Takahashi, Hideyo; Ikegami, Shiro
Synlett, 2002 , # 12 p. 2031 - 2034
Title/Abstract Full Text View citing articles Show Details
Yamada, Yoichi M.A.; Tabata, Hidetsugu; Ichinohe, Masato; Takahashi, Hideyo; Ikegami, Shiro
Tetrahedron, 2004 , vol. 60, # 18 p. 4087 - 4096
反应条件
1: KCN / ethanol / 0.58 h / 95 °C
2: 930 mg / Cu(OAc)2; NH4NO3; glacial acetic acid / H2O / 1 h / 140 °C
View Scheme
参考文献
Lombardino; Wiseman
Journal of Medicinal Chemistry, 1974 , vol. 17, # 11 p. 1182 - 1188
