4-(甲基巯基)苯甲醛合成路线 （共 113 条）
反应条件
sodium methylate; toluene-4-sulfonic acid; Nalco silica sol 1060
反应条件
potassium cyanide; water in methanol Reflux;
参考文献
Assadieskandar, Amir; Amini, Mohsen; Salehi, Marjan; Sadeghian, Hamid; Alimardani, Maliheh; Sakhteman, Amirhossein; Nadri, Hamid; Shafiee, Abbas
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 24 p. 7160 - 7166
反应条件
1: 98 percent / NaOH; LiBr / dioxane 2: 83 percent / TsOH / xylene 3: 92 percent / conc. H2SO4 / trifluoroacetic acid / 20 °C 4: BH2-THF View Scheme
参考文献
Schulze, Oliver; Schmidt, Ulrich; Voss, Juergen; Nebeling, Bruno; Adiwidjaja, Gunadi; Scharwaechter, Klaus
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 8 p. 2105 - 2111
反应条件
tert.-butylhydroperoxide; sodium hydroxide; (CTA)2SO4 T=20°C; 20 h;
参考文献
Fringuelli; Pellegrino; Piermatti; Pizzo
Synthetic Communications, 1994 , vol. 24, # 18 p. 2665 - 2673
反应条件
1: With potassium carbonate Horner-Wadsworth-Emmons olefination; 6 h; Neat (no solvent)high-speed ball milling; 2: With Oxonereg; 12 h; Neat (no solvent)high-speed ball milling; optical yield given as percent dediastereoselective reaction;
参考文献
Shearouse, William C.; Korte, Chelsea M.; Mack, James
Green Chemistry, 2011 , vol. 13, # 3 p. 598 - 601
反应条件
1: 16.85 g / piperidine; pyridine / 3 h / Heating 2: 100 mg / H2 / Pd/C / ethyl acetate; ethanol / 168 h / 20 °C View Scheme
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
Tetraethylammonium formate T=95 - 100°C;
参考文献
Englert; Gerlach; Goegelein; Hartung; Heitsch; Mania; Scheidler
Journal of Medicinal Chemistry, 2001 , vol. 44, # 7 p. 1085 - 1098
反应条件
1: 91 percent / piperidine / pyridine / 5 h / 110 °C 2: 66 percent / Mg / methanol / 2 h / 25 - 55 °C 3: 82 percent / PPA / 0.17 h / 100 °C View Scheme
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
sodium hydroxide in N,N-dimethyl-formamide
参考文献
Fletcher; Namkung; Pan; Cole
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1113 - 1115
反应条件
1: NaOH / dimethylformamide 2: dimethylsulfoxide / Heating View Scheme
参考文献
Fletcher; Namkung; Pan; Cole
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1113 - 1115
