2-羟基-6-三氟甲基吡啶合成路线 （共 6 条）
反应条件
hydrogenchloride in water
参考文献
Zeneca Limited
Patent: US6143899 A1, 2000 ;
反应条件
potassium hydroxide; sodium chloride
参考文献
Zeneca Limited
Patent: US5973159 A1, 1999 ;
参考文献
Zeneca Limited
Patent: US5973159 A1, 1999 ;
反应条件
potassium hydroxide in water
反应条件
Ag2CO3 in dichloromethane 24 h; Darkness;
参考文献
SYNGENTA LIMITED; BHONOAH, Yunas; ELLIOTT, Alison Clare; GAULIER, Steven; LING, Kenneth; MITCHELL, Glynn; MORRIS, James Alan; RZEPA, Paula Rocha; VINER, Russell Colin
Patent: WO2013/50421 A1, 2013 ;
Location in patent: Page/Page column 59 ;
反应条件
phosphorus pentachloride; sulfuric acid; nitric acid; trichlorophosphate 1.) 50 deg C, 18 h, 2.) 90 deg C, 18 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Robinson, Ralph P.; Donahue, Kathleen M.; Son, Paul S.; Wagy, Steven D.
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 2 p. 287 - 293
