1: 3-methyl-3-(hydroxy-methyl)-oxetane With sodium hydride in tetrahydrofuran; mineral oil T=0 - 20°C; Inert atmosphere; 2: dimethyl sulfate in tetrahydrofuran; mineral oil T=0 - 20°C; Inert atmosphere;

1: 81 percent / pyrydine / CHCl3 2: 1.) NaH / 1.) THF, reflux, overnight, 2.) THF, reflux, 24 h View Scheme

in tetrahydrofuran Heating;

sodium 1.) THF, reflux, 2.) 35 deg C, 2 h; Yield given. Multistep reaction;

sodium hydride 1.) THF, reflux, overnight, 2.) THF, reflux, 24 h; Multistep reaction;