4-氟-4'-甲氧基二苯甲酮合成路线 （共 26 条）
反应条件
lithium aluminium tetrahydride
参考文献
Wang, Hui; Zhu, Xingfei; Lu, Yangning; Li, Yue; Gao, Xiang
Chinese Journal of Chemistry, 2011 , vol. 29, # 6 p. 1180 - 1184
参考文献
Cowart, Marlon; Faghih, Ramin; Curtis, Michael P.; Gfesser, Gregory A.; Bennani, Youssef L.; Black, Lawrence A.; Pan, Liping; Marsh, Kennan C.; Sullivan, James P.; Esbenshade, Timothy A.; Fox, Gerard B.; Hancock, Arthur A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 38 - 55
参考文献
Gabbutt, Christopher D.; Heron, B. Mark; McCreary, Janice M.; Thomas, David A.
Journal of Chemical Research - Part S, 2002 , # 2 p. 69 - 71
反应条件
1: 1.) Mg / 2.) ether, 2.) ether, reflux, 4 h
2: 85 percent / BBr3 / CH2Cl2 / 1 h / Ambient temperature
3: KOH / ethanol / 20 h / Heating
View Scheme
参考文献
Shani; Gazit; Livshitz; Biran
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1504 - 1511
反应条件
sodium hydride in tetrahydrofuran
4 h; Heating;
参考文献
Gazit; Livshitz; Shani
Steroids, 1987 , vol. 48, # 1-2 p. 73 - 84
反应条件
potassium hydroxide in water; dimethyl sulfoxide
T=60°C; 18 h;
参考文献
Ridd, John H.; Yousaf, Taher I.; Rose, John B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988 , p. 1729 - 1734
