4,4'-二氟二苯甲酮合成路线 （共 115 条）
反应条件
cesium fluoride in N,N-dimethyl-formamide T=-10 - 20°C; 6 h;
参考文献
Journal of Organic Chemistry, , vol. 65, # 26 p. 8848 - 8856
反应条件
in dimethyl sulfoxide
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4859693 A1, 1989 ;
反应条件
bismuth trifluoromethanesulphonate in methanol 24 h; Heating;
参考文献
Leonard, Nicholas M.; Oswald, Matthew C.; Freiberg, Derek A.; Nattier, Bryce A.; Smith, Russell C.; Mohan, Ram S.
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5202 - 5207
反应条件
trifluorormethanesulfonic acid; trimethyl orthoformate in nitromethane 4 h; Heating;
参考文献
Thurkauf, Andrew; Jacobson, Arthur E.; Rice, Kenner C.
Synthesis, 1988 , # 3 p. 233 - 234
反应条件
bis(2-methoxyethyl)aminosulfur trifluoride T=90°C; 24 h; Neat (no solvent)Inert atmosphere;
参考文献
Chang, Ying; Lee, Hyelee; Bae, Chulsung; Hughes, David
Organic Syntheses, 2010 , vol. 87, p. 245 - 252
反应条件
hydroxylamine hydrochloride in ethanol Heating;
参考文献
Zhang; Joseph; Bowen; Flippen-Anderson; Dersch; Rothman; Jacobson; Rice
Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3937 - 3945
反应条件
acetylene in benzene T=55°C; 4 h;
参考文献
Botteghi, Carlo; Marchetti, Mauro; Paganelli, Stefano; Persi-Paoli, Francesco
Tetrahedron, 2001 , vol. 57, # 8 p. 1631 - 1637
反应条件
1: in tetrahydrofuran T=20°C; 24 h; Inert atmosphere; 2: With water; ammonium chloride in tetrahydrofuran; diethyl ether Saturated solution;
参考文献
Boettcher, Christoph; Zeyat, Gehad; Ahmed, Saleh A.; Irran, Elisabeth; Rueck-Braun, Karola; Cordes, Thorben; Elsner, Cord; Zinth, Wolfgang
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. A25
反应条件
1: acetylene With ethylmagnesium bromide in tetrahydrofuran T=0 - 25°C; 1.16667 h; 2: 1,1-di(p-fluorophenyl)-ketone in tetrahydrofuran T=23 - 25°C; 5 h;
参考文献
Wang, Jia; Zhu, Hai-Tao; Li, Ying-Xiu; Wang, Li-Jing; Qiu, Yi-Feng; Qiu, Zi-Hang; Zhong, Mei-Jin; Liu, Xue-Yuan; Liang, Yong-Min
Organic Letters, 2014 , vol. 16, # 8 p. 2236 - 2239
反应条件
in tetrahydrofuran; xylene T=-5 - 20°C;
参考文献
Teral, Yannick; Roubaud, Gabriel; Aubert, Claude; Faure, Robert; Campredon, Mylene
Australian Journal of Chemistry, 2005 , vol. 58, # 7 p. 517 - 521
