1-(2-三氟甲基苯基)-吡咯-2,5-二酮合成路线 （共 3 条）
反应条件
sulfuric acid in dimethyl sulfoxide; toluene T=130°C;
参考文献
Albemarle Corporation; University of Southern Mississippi
Patent: EP984931 B1, 2005 ;
Location in patent: Page 9 ;
反应条件
1: in diethyl ether T=20°C; 2: With sodium acetate; acetic anhydride T=120°C;
参考文献
Chen, Hai-Jun; Liu, Yong; Wang, Li-Na; Shen, Qiang; Li, Jia; Nan, Fa-Jun
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 9 p. 2876 - 2879
反应条件
1: diethyl ether / 20 °C 2: conc. H2SO4 / toluene; dimethylsulfoxide / 130 °C View Scheme
参考文献
Miller, Chris W.; Sonny Joensson; Hoyle, Charles E.; Viswanathan, Kalyanaraman; Valente, Edward J.
Journal of Physical Chemistry B, 2001 , vol. 105, # 14 p. 2707 - 2717
