(2-氧代-2-苯乙基)膦酸二乙酯合成路线 （共 61 条）
反应条件
T=180°C; 48 h; Inert atmosphere;
参考文献
Dunny, Elizabeth; Doherty, William; Evans, Paul; Malthouse, J. Paul G.; Nolan, Derek; Knox, Andrew J.S.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 17 p. 6638 - 6650
反应条件
dihydrogen peroxide; sodium carbonate in methanol T=35°C; 168 h;
参考文献
Chemische Berichte, , vol. 118, # 9 p. 4099 - 4130
反应条件
n-butyllithium T=-78°C; 2 h; Inert atmosphere;
参考文献
Sabitha, Gowravaram; Padmaja, Pannala; Yadav, Jhillu S.
Helvetica Chimica Acta, 2008 , vol. 91, # 12 p. 2235 - 2239
参考文献
Fedorova, G. K.; Anan'eva, L. G.; Yakovchuk, O. A.
J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 7 p. 1481 - 1484,1321 - 1323
反应条件
hydrogenchloride; acetone 3 h; Ambient temperature;
参考文献
Corbel, Bernard; Medinger, Luc; Haelters, Jean Pierre; Sturtz, Georges
Synthesis, 1985 , # 11 p. 1048 - 1051
反应条件
1: 1) MgCl2, Et3N / 1) toluene, room temperature, 2 h, 2) room temperature, 6 h 2: p-TsOH / H2O / 4 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 26, # 13 p. 2487 - 2496
反应条件
toluene-4-sulfonic acid 4 h; Heating; Yield given;
参考文献
Synthetic Communications, , vol. 25, # 18 p. 2865 - 2869
反应条件
T=90°C; Arbuzov reaction; 0.283333 h;
参考文献
Moorhoff, Cornelis M.
Synthetic Communications, 2003 , vol. 33, # 12 p. 2069 - 2086
反应条件
1: 1) MgCl2, Et3N / 1) toluene, room temperature, 2 h, 2) room temperature, 6 h 2: p-TsOH / H2O / 4 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 26, # 13 p. 2487 - 2496
反应条件
potassium tert-butylate in dimethyl sulfoxide 0.5 h; Ambient temperature;
参考文献
Russell, Glen A.; Ngoviwatchai, Preecha
Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1836 - 1842
