7-Boc-5,6,7,8-四氢咪唑并[1,2-a]吡嗪合成路线 （共 5 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 21.5 h; Heating / reflux;
参考文献
Castro Pineiro, Jose Luis; Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Shaw, Duncan Edward; Swain, Christopher John
Patent: US2003/236250 A1, 2003 ;
Location in patent: Page 40 ;
反应条件
triethylamine in dichloromethane T=20°C; 48 h;
参考文献
WO2010/125101 A1, ;
Page/Page column 58-59 ;
WO 2010/125101 A1
反应条件
tin(IV) chloride in 1,3,5-trimethyl-benzene Reflux;
参考文献
WO2009/158394 A1, ;
Page/Page column 69; 71 ;
反应条件
N-bromosuccinmide in tetrachloromethane 0.5 h; Reflux;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2009/158394 A1, 2009 ;
Location in patent: Page/Page column 69; 71 ;
反应条件
N-bromosuccinmide in tetrachloromethane
0.5 h; Reflux;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2009/158394 A1, 2009 ;
Location in patent: Page/Page column 69; 71 ;
