甲基7-(5-氧代-1-环戊烯-1-基)庚酸酯合成路线 （共 105 条）
反应条件
lithium carbonate in N,N-dimethyl-formamide
0.5 h; Heating;
参考文献
Holland; Ratemi; Contreras
Canadian Journal of Chemistry, 1994 , vol. 72, # 1 p. 1 - 5
反应条件
tetraethylammonium p-toluenesulfonate; acetic acid
参考文献
Shono,T. et al.
Journal of the American Chemical Society, 1975 , vol. 97, p. 6144 - 6147
反应条件
hydrogenchloride in methanol; water
8 h; Heating;
参考文献
Kaji, Aritsune
Phosphorus and Sulfur and the Related Elements, 1985 , vol. 23, p. 211 - 222
反应条件
zinc silver in methanol
48 h; Ambient temperature;
参考文献
Novak; Baan; Marosfalvi; Szantay
Chemische Berichte, 1980 , vol. 113, # 9 p. 2939 - 2949
反应条件
1: 58 g / p-toluenesulfonic acid / benzene / 6 h / Heating
View Scheme
参考文献
Lapitskaya, M. A.; Manukina, T. A.; Nozdracheva, A. T.; Sheimina, L. G.; Pivnitskii, K. K.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 261 - 265
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 2 p. 294 - 299
反应条件
1: 101 g / pyridine / 1.) RT, 24 h, 2.) reflux, 4 h
2: 40 g / 10percent aq. NaOH / 4 h / Heating
3: 55 percent / 60percent H2SO4 / 2.5 h / 130 °C
4: 70 percent / polyphosphoric acid / 2.5 h / 100 °C
5: 22.5 g / 15percent methanolic HCl / 30 h / Ambient temperature
View Scheme
参考文献
Thakur, S. B.; Jadhav, K. S.; Bhattacharyya, S. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 675 - 683
反应条件
1: LiBr, Li2CO3 / DMF, reflux, 0.5h
2: 95.8 percent / pyridine; ethanol / 22 h / Ambient temperature
3: 2N HCl / acetone / 5 h / Heating
4: 80.6 percent / p-toluenesulfonic acid / 5 h / Heating
View Scheme
参考文献
Bernady; Poletto; Nocera; et al.
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4702 - 4715
反应条件
1: (i) H5IO6, Et2O, (ii) CrO3, aq. H2SO4, acetone
2: diethyl ether
View Scheme
参考文献
Sih; Salomon; Price; Sood; Peruzzotti
Journal of the American Chemical Society, 1975 , vol. 97, # 4 p. 857 - 865
反应条件
1: Cu
2: aq. HCl
3: NaOMe
View Scheme
参考文献
Wenkert,E. et al.
Journal of the American Chemical Society, 1978 , vol. 100, p. 1267 - 1273
反应条件
1: aq. HCl
2: NaOMe
View Scheme
参考文献
Wenkert,E. et al.
Journal of the American Chemical Society, 1978 , vol. 100, p. 1267 - 1273
