甲基7-(5-氧代-1-环戊烯-1-基)庚酸酯合成路线 （共 105 条）
反应条件
1: 6.2 g / Jones' reagent / acetone / 0.5 h / 0 - 5 °C
2: 8.7 g / Br2 / CCl4 / 2 h / Ambient temperature
3: 6.1 g / NaOH / H2O / 6 h / Heating
4: 22.5 g / 15percent methanolic HCl / 30 h / Ambient temperature
View Scheme
参考文献
Thakur, S. B.; Jadhav, K. S.; Bhattacharyya, S. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 675 - 683
反应条件
1: 6.1 g / NaOH / H2O / 6 h / Heating
2: 22.5 g / 15percent methanolic HCl / 30 h / Ambient temperature
View Scheme
参考文献
Thakur, S. B.; Jadhav, K. S.; Bhattacharyya, S. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 675 - 683
反应条件
1: 7.8 g / NaOH/85percent aq. MeOH / 2.5 h / Heating
2: 6.2 g / Jones' reagent / acetone / 0.5 h / 0 - 5 °C
3: 8.7 g / Br2 / CCl4 / 2 h / Ambient temperature
4: 6.1 g / NaOH / H2O / 6 h / Heating
5: 22.5 g / 15percent methanolic HCl / 30 h / Ambient temperature
View Scheme
参考文献
Thakur, S. B.; Jadhav, K. S.; Bhattacharyya, S. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 675 - 683
反应条件
2: (i) MeLi, Et2O, (ii) /BRN= 1905070/, HMPT, THF
3: AgClO4 / benzene
View Scheme
参考文献
Wakamatsu,T. et al.
Synthetic Communications, 1978 , vol. 8, p. 319 - 326
反应条件
1: (i) MeLi, Et2O, (ii) /BRN= 1905070/, HMPT, THF
2: AgClO4 / benzene
View Scheme
参考文献
Wakamatsu,T. et al.
Synthetic Communications, 1978 , vol. 8, p. 319 - 326
反应条件
1: H2 / Pd-CaCO3
2: ZnCl2
3: (i) HgCl2, CdCO3, (ii) K2CO3, MeOH
View Scheme
参考文献
Ide,J. et al.
Bulletin of the Chemical Society of Japan, 1978 , vol. 51, # 3 p. 939 - 940
反应条件
1: CuCl, DCC
2: H2 / Pd-CaCO3
3: ZnCl2
4: (i) HgCl2, CdCO3, (ii) K2CO3, MeOH
View Scheme
参考文献
Ide,J. et al.
Bulletin of the Chemical Society of Japan, 1978 , vol. 51, # 3 p. 939 - 940
反应条件
sodium carbonate in xylene
Heating; Yield given;
参考文献
Lakhvich; Kozinets
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 1 p. 42 - 46
反应条件
1: 30percent aq.H2SO4 / aq. acetic acid / 16 h / Heating
2: 58 g / p-toluenesulfonic acid / benzene / 6 h / Heating
View Scheme
参考文献
Lapitskaya, M. A.; Manukina, T. A.; Nozdracheva, A. T.; Sheimina, L. G.; Pivnitskii, K. K.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 261 - 265
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 2 p. 294 - 299
反应条件
1: tert-butyl hypochlorite / CHCl3 / 2 h / -10 °C
2: Na2CO3 / xylene / Heating
View Scheme
参考文献
Lakhvich; Kozinets
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 1 p. 42 - 46
