4-丁基-3,5-二甲基-1H-吡咯-2-羧酸乙酯合成路线 （共 15 条）
反应条件
acetic acid; zinc 1 h; Heating;
参考文献
Berezin, M. V.; Semeikin, A. S.; V'yugin, A. I.; Krestov, G. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 449 - 453
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 495 - 499
反应条件
in acetic acid Cyclization; 2 h; Heating;
参考文献
Lash, Timothy D.
Tetrahedron, 1998 , vol. 54, # 3-4 p. 359 - 374
反应条件
1: 64.5 percent / potassium carbonate / acetone / 20 h / Heating 2: 79 percent / acetic acid / 2 h / Heating View Scheme
参考文献
Klyueva; Lebedev; Nikitin; Semeikin
Russian Journal of General Chemistry, 2006 , vol. 76, # 11 p. 1848 - 1850
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Fischer; Bertl
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 37,49
反应条件
diethyl ether; ethylmagnesium bromide Erwaermen des Reaktionsgemisches mit Chlorokohlensaeure-aethylester;
参考文献
Fischer; Bertl
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 37,49
反应条件
sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium acetate; zinc; sodium nitrite 2.) 60 deg C, 1 h, reflux, 2 h; 3.) THF, RT, 4 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fujii, Hiroshi; Yoshimura, Tetsuhiko; Kamada, Hitoshi
Tetrahedron Letters, 1997 , vol. 38, # 8 p. 1427 - 1430
反应条件
1: AlCl3 2: hydrazine hydrate; sodium ethylate / 170 °C 3: ethyl magnesium bromide; diethyl ether / Erwaermen des Reaktionsgemisches mit Chlorokohlensaeure-aethylester View Scheme
参考文献
Fischer; Bertl
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 37,49
反应条件
sodium acetate; zinc 1.) acetic acid, 80 deg C, 40 min; 2.) acetic acid, 20 min, 95-105 deg C; Yield given. Multistep reaction;
参考文献
Lecas-Nawrocka, Alexandra; Levisalles, Jacques; Mariacher, Claire; Renko, Zafiarisoa; Rose, Eric
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2054 - 2058
参考文献
Akopova; Zdanovich; Akopov; Aleksandrov; Pashkova
Journal of Structural Chemistry, 2001 , vol. 42, # 1 p. 43 - 50
反应条件
1: 66 percent / KOH / ethane-1,2-diol / 1 h / Heating 2: 88 percent / POCl3 / 2 h View Scheme
参考文献
Berezin; Semeikin; Antina; Pashanova; Lehedeva; Bukushina
Russian Journal of General Chemistry, 1999 , vol. 69, # 12 p. 1949 - 1955
