4,4'-二甲基苯偶酰合成路线 （共 111 条）
反应条件
1: hydrazine hydrate
3: 80 - 90 °C
4: water
View Scheme
参考文献
Gilman; Adams
Recueil des Travaux Chimiques des Pays-Bas, 1929 , vol. 48, p. 465
反应条件
1: hydrazine hydrate
View Scheme
参考文献
Curtius; Kastner
Journal fuer Praktische Chemie (Leipzig), 1911 , vol. <2> 83, p. 225
反应条件
1: 50.7 percent / aq. NaOH / ethanol / 1 h / Ambient temperature
2: 1) HI, 2) 40 percent aq. NaHSO3 / 1) reflux, 20 min, 2) reflux, 10 min
View Scheme
参考文献
Horspool, William M.; Khalaf, Abedawn I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1147 - 1152
反应条件
1: 68.2 percent / aq. NaOH / ethanol / 1 h / Ambient temperature
2: 1) HI, 2) 40 percent aq. NaHSO3 / 1) reflux, 20 min, 2) reflux, 10 min
View Scheme
参考文献
Horspool, William M.; Khalaf, Abedawn I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1147 - 1152
反应条件
in ethanol
0.5 h; Heating;
参考文献
Ohta, Akihiro; Inoue, Masami; Yamada, Junichi; Yamada, Yasuhiko; Kurihara, Teruo; Honda, Toshihiro
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 103 - 106
反应条件
ethanol; ethylenediamine
参考文献
van Alphen
Recueil des Travaux Chimiques des Pays-Bas, 1935 , vol. 54, p. 443,445
参考文献
van Alphen
Recueil des Travaux Chimiques des Pays-Bas, 1935 , vol. 54, p. 443,445
反应条件
sodium
1.) THF, reflux, 7-11 h, 2.) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Singh, M. S.; Mehrotra, K. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1289 - 1290
反应条件
C8K in tetrahydrofuran
5 h; Ambient temperature;
参考文献
Tamarkin, Dov; Benny, Daphna; Rabinovitz, Mordecai
Angewandte Chemie, 1984 , vol. 96, # 8 p. 594 - 595
反应条件
methanol; sodium methylate
参考文献
Backer; Stevens
Recueil des Travaux Chimiques des Pays-Bas, 1940 , vol. 59, p. 899,906
