3-氯-6-甲基苯并[b]噻吩-2-甲酰氯合成路线 （共 5 条）
反应条件
thionyl chloride; N-benzyl-N,N,N-triethylammonium chloride T=140°C; 3 h;
参考文献
Sidorenko, T.N.; Terent'eva, G.A.; Raida, V.S.; Andrienko, O.S.; Savinykh, Yu.V.; Aksenov, V.S.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 12 p. 1246 - 1250
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 12 p. 1618 - 1622
反应条件
pyridine; thionyl chloride T=140°C; 0.5 h;
参考文献
Ried, Walter; Oremek, Gerhard; Ocakcioglu, Belkis
Liebigs Annalen der Chemie, 1980 , # 9 p. 1424 - 1427
反应条件
thionyl chloride; [BMmorf][Cl] T=140°C; 2.5 h;
参考文献
Obushak; Matiichuk; Martyak
Chemistry of Heterocyclic Compounds, 2003 , vol. 39, # 7 p. 878 - 884
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane T=0 - 20°C; 3 h;
参考文献
Li, Lianhai; Berthelette, Carl; Chateauneuf, Anne; Ouellet, Marc; Sturino, Claudio F.; Wang, Zhaoyin
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 24 p. 7440 - 7443
反应条件
1: 85 percent / 3 h / 80 °C 2: 90 percent / methanol; H2O / 1 h / Heating View Scheme
参考文献
Hoechst Aktiengesellschaft
Patent: US5350751 A1, 1994 ;
US 5350751 A
