4-氯-7-三氟甲基喹啉合成路线 （共 23 条）
反应条件
phosphorus pentachloride; trichlorophosphate T=130°C;
参考文献
Journal of the American Chemical Society, , vol. 69, p. 371,373
反应条件
in acetonitrile T=0 - 23°C;
参考文献
Gregory Reid; Reny Runge, Jean H.
Tetrahedron Letters, 1990 , vol. 31, # 8 p. 1093 - 1096
反应条件
1: 95 percent / NH4HCO2 / 5percent Pd/C / methanol / Heating 3: 10 percent View Scheme
参考文献
Tetrahedron Letters, , vol. 31, # 8 p. 1093 - 1096
反应条件
1: diphenyl ether / 1 h / Heating 2: POCl3 / 1.17 h / 100 - 110 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926
反应条件
1: 2 N NaOH / Heating 2: diphenyl ether / 1 h / Heating 3: POCl3 / 1.17 h / 100 - 110 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926
反应条件
1: diphenyl ether / Heating 2: 2 N NaOH / Heating 3: diphenyl ether / 1 h / Heating 4: POCl3 / 1.17 h / 100 - 110 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926
反应条件
1: 100 percent / 1 h / 90 - 110 °C 2: diphenyl ether / Heating 3: 2 N NaOH / Heating 4: diphenyl ether / 1 h / Heating 5: POCl3 / 1.17 h / 100 - 110 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926
反应条件
1: diphenyl ether / 0.08 h / 300 °C / microwave irradiation 2: POCl3 / 3 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 4 p. 1015 - 1018
反应条件
2: 10 percent View Scheme
参考文献
Tetrahedron Letters, , vol. 31, # 8 p. 1093 - 1096
参考文献
Gregory Reid; Reny Runge, Jean H.
Tetrahedron Letters, 1990 , vol. 31, # 8 p. 1093 - 1096
