5-氨基-3-氯-吡嗪-2-甲腈合成路线 （共 2 条）
反应条件
copper(l) iodide; 18-crown-6 ether; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=20 - 200°C; 3.5 h; Inert atmosphere;
参考文献
CANCER RESEARCH TECHNOLOGY LIMITED; COLLINS, Ian; LAINCHBURY, Michael; MATTHEWS, Thomas Peter; READER, John Charles
Patent: WO2013/68755 A1, 2013 ;
Location in patent: Page/Page column 67, 68 ;
反应条件
carbon in o-xylene T=160°C; 20 h;
参考文献
Tao, Zhi-Fu; Lin, Nan-Horng; Wang, Le; Sowin, Thomas J.
Patent: US2005/96324 A1, 2005 ;
Location in patent: Page/Page column 10 ;
US 20050096324 A1
