4-氯喹唑啉-2-甲酸乙酯合成路线 (共 2 条)
反应条件
thionyl chloride; N,N-dimethyl-formamide in chloroform 4.5 h; Reflux;
参考文献
Yuan, Yunyun; Elbegdorj, Orgil; Beletskaya, Irina O.; Selley, Dana E.; Zhang, Yan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5045 - 5048
反应条件
1: With palladium 10 on activated carbon; hydrogen; triethylamine in ethanol
T=20°C; P=775.743 Torr; 4 h;
2: in anhydrous xylene
3 h; Reflux;
参考文献
Yuan, Yunyun; Elbegdorj, Orgil; Beletskaya, Irina O.; Selley, Dana E.; Zhang, Yan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5045 - 5048