1: 1-amino-2-bromo-4-nitrobenzene With hydrogenchloride; sodium nitrite in water T=0°C; 1 h; 2: copper (I) cyanide; potassium cyanide in water T=50°C; 1 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2009/3077 A1, 2008 ;
Location in patent: Page/Page column 139 ;
1: 1-amino-2-bromo-4-nitrobenzene With hydrogenchloride; sodium nitrite in water T=0°C; 1 h; Inert atmosphere; 2: copper (I) cyanide With potassium cyanide in water T=50°C; 1 h; Inert atmosphere;
参考文献
Den Heeten, Rene; Van Der Boon, Leon J. P.; Broere, Daniel L. J.; Janssen, Elwin; De Kanter, Frans J. J.; Ruijter, Eelco; Orru, Romano V. A.
European Journal of Organic Chemistry, 2012 , # 2 p. 275 - 280
Den Heeten, Rene; Van Der Boon, Leon J. P.; Broere, Daniel L. J.; Janssen, Elwin; De Kanter, Frans J. J.; Ruijter, Eelco; Orru, Romano V. A.
European Journal of Organic Chemistry, 2012 , # 2 p. 275 - 280
