5-甲氧基吲哚-3-乙酸合成路线 （共 20 条）
反应条件
potassium hydroxide T=100°C;
参考文献
Tsotinis, Andrew; Afroudakis, Pandelis A.; Davidson, Kathryn; Prashar, Anjali; Sugden, David
Journal of Medicinal Chemistry, 2007 , vol. 50, # 25 p. 6436 - 6440
反应条件
potassium hydroxide in tetrahydrofuran; water T=20°C;
参考文献
Kai, Kenji; Horita, Junko; Wakasa, Kyo; Miyagawa, Hisashi
Phytochemistry, 2007 , vol. 68, # 12 p. 1651 - 1663
反应条件
1: tetrahydrofuran / 2 h / 0 °C 2: triethylamine / tetrahydrofuran / 4 h / 20 °C 3: 94 percent / NaH2PO2*H2O / palladium on activated charcoal / dioxane; H2O / 48 h / 20 °C 4: 100 percent / KOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
1: triethylamine / tetrahydrofuran / 4 h / 20 °C 2: 94 percent / NaH2PO2*H2O / palladium on activated charcoal / dioxane; H2O / 48 h / 20 °C 3: 100 percent / KOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
1: 94 percent / NaH2PO2*H2O / palladium on activated charcoal / dioxane; H2O / 48 h / 20 °C 2: 100 percent / KOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
1: 6 M NaOH / ethanol / 1 h / Heating 2: 1 M HCl / 1.5 h / Heating 3: Cu2Cr2O5 / quinoline / 2 h / Heating 4: 6 M NaOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 4 p. 638 - 648
反应条件
1: 1 M HCl / 1.5 h / Heating 2: Cu2Cr2O5 / quinoline / 2 h / Heating 3: 6 M NaOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 4 p. 638 - 648
反应条件
sodium hydroxide in ethanol 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 4 p. 638 - 648
反应条件
1: 1.) 12 M HCl, NaNO2, 2.) 6 M KOH, 3.) H2SO4 2: 6 M NaOH / ethanol / 1 h / Heating 3: 1 M HCl / 1.5 h / Heating 4: Cu2Cr2O5 / quinoline / 2 h / Heating 5: 6 M NaOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 4 p. 638 - 648
反应条件
sodium acetate; hydrazine hydrate in V methoxymethyl ester
参考文献
Journal of the American Chemical Society, , vol. 134, # 26 p. 10815 - 10818
