(4-硝基苯基)(2-噻吩基)甲酮合成路线 （共 15 条）
反应条件
sodium iodide; dichloro bis(acetonitrile) palladium(II) in acetone 20°C, 10 min; thin-layer chromy., UV spectroscopy;
参考文献
Bumagin, N.A.; Kalinovskii, I.O.; Beletskaya, I.P.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, # 10 p. 2144 - 2149
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 10 p. 2347 - 2352
反应条件
silica gel supported aluminium trichloride T=60°C; Friedel Crafts acylation; 2.5 h; regioselective reaction;
参考文献
Parvanak Boroujeni, Kaveh
Turkish Journal of Chemistry, 2010 , vol. 34, # 4 p. 621 - 630
反应条件
sodium iodide; dichloro bis(acetonitrile) palladium(II) in acetone acyldemetallation by stirring a mixt. of acyl chloride, R2Hg, NaI and Pd catalyst in acetone, room temp., 10 min; monitoring by UV; dilution (H2O); extraction (ether); washing (aq. NaI); drying over MgSO4; evapn.;
参考文献
Bumagin, N. A.; More, P. G.; Beletskaya, I. P.
Journal of Organometallic Chemistry, 1989 , vol. 365, p. 379 - 388
反应条件
iodine; magnesium in tetrahydrofuran 1.) reflux, 3 h; 2.) 20 deg C, 45 min then 22 deg C, 3 h;
参考文献
Stoner, Eric J.; Cothron, Darlene A.; Balmer, Mary K.; Roden, Brian A.
Tetrahedron, 1995 , vol. 51, # 41 p. 11043 - 11062
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in 1,4-dioxane Suzuki coupling; 2 h; Heating;
参考文献
Rahman, Obaidur; Kihlberg, Tor; Langstroem, Bengt
European Journal of Organic Chemistry, 2004 , # 3 p. 474 - 478
反应条件
quinoline; copper oxide-chromium oxide; copper(II) oxide
参考文献
Goncalves et al.
Journal of Organic Chemistry, 1952 , vol. 17, p. 705,709
反应条件
1: diethyl ether; benzene 2: copper oxide; copper oxide-chromium oxide; quinoline View Scheme
参考文献
Goncalves et al.
Journal of Organic Chemistry, 1952 , vol. 17, p. 705,709
反应条件
potassium phosphate; palladium diacetate T=20°C; 3 h;
参考文献
Zhou, Qing; Wei, Shaohua; Han, Wei
Journal of Organic Chemistry, 2014 , vol. 79, # 3 p. 1454 - 1460
反应条件
bis(η3-allyl-μ-chloropalladium(II)) in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=20°C; 0.0333333 h;
参考文献
Bumagin, N. A.; Bumagina, I. G.; Kashin, A. N.; Beletskaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1982 , p. 977 - 981
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 6 p. 1131 - 1137
反应条件
1: thionyl chloride / Behandeln des Reaktionsprodukts in Benzol mit Thiophen und Zinn(IV)-chlorid 2: copper oxide; copper oxide-chromium oxide; quinoline View Scheme
参考文献
Weinmayr
Journal of the American Chemical Society, 1952 , vol. 74, p. 4353,4356
