1,6-二氢-6-氧代-2-(3-吡啶)-5-嘧啶羧酸乙酯合成路线 （共 2 条）
反应条件
1: pyridine-3-carboximidamide With ethanol; sodium ethanolate T=20°C; 0.166667 h; 2: diethyl 2-ethoxymethylenemalonate in ethanol T=0 - 20°C; 5 h; 3: With hydrogenchloride in ethanol; water pH=5;
参考文献
US2011/105520 A1, ;
Page/Page column 44-45 ;
反应条件
1: With thionyl chloride; N,N-dimethyl-formamide T=20°C; 2: With potassium carbonate in water Cooling;
参考文献
COATS, STEVEN J.; BIAN, HAIYAN; CONNOLLY, PETER J.; BIGNAN, GILLES; CAI, CHAOZHONG; DAX, SCOTT L.; DECORTE, BART L.; LIN, SHU-CHEN; LIU, LI; MACIELAG, MARK J.; PITIS, PHILIP M.; ZHANG, YUE-MEI; ZHU, BIN; HE, WEI
Patent: US2011/105520 A1, 2011 ;
Location in patent: Page/Page column 44-45 ;
