1,2,3,4-四氢喹喔啉合成路线 （共 34 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 80°C; 4 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; SHAN, Weifang; GAVAI, Ashvinikumar V.; BALOG, James Aaron
Patent: WO2014/47390 A1, 2014 ;
Location in patent: Paragraph 00229; 00230 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 1 h; 2: With water in tetrahydrofuran T=0°C;
参考文献
Tuerdi, Huji; Chao, Hannguang J.; Qiao, Jennifer X.; Wang, Tammy C.; Gungor, Timur
Patent: US2005/261244 A1, 2005 ;
Location in patent: Page/Page column 53 ;
US 20050261244 A1
反应条件
[{(η5-C5Me5)RhCl}2(μ-Cl)2]; potassium iodide T=40°C; 12 h;
参考文献
Wu, Jianjun; Wang, Chao; Tang, Weijun; Pettman, Alan; Xiao, Jianliang
Chemistry - A European Journal, 2012 , vol. 18, # 31 p. 9525 - 9529
参考文献
Bristol-Myers Squibb Company
Patent: US6011029 A1, 2000 ;
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; potassium carbonate in xylene T=140°C; 120 h;
参考文献
Todd Eary; Clausen, Dane
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6899 - 6902
反应条件
1: H2 / Pd/C 2: 30 percent / K2CO3; [Cp*IrCl2]2 / xylene / 120 h / 140 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 38 p. 6899 - 6902
反应条件
tetrabutyl-ammonium chloride T=60°C; 1 h; Ionic liquid;
参考文献
Monopoli, Antonio; Cotugno, Pietro; Cortese, Marina; Calvano, Cosima Damiana; Ciminale, Francesco; Nacci, Angelo
European Journal of Organic Chemistry, 2012 , # 16 p. 3105 - 3111
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; sodium hydrogencarbonate in 1,3,5-trimethyl-benzene T=140°C; 17 h; Inert atmosphereHeating;
参考文献
Lorentz-Petersen, Linda L. R.; Nordstrom, Lars Ulrik; Madsen, Robert
European Journal of Organic Chemistry, 2012 , # 34 p. 6752 - 6759
反应条件
hydrogen bromide T=140°C; 60 h;
参考文献
Shishkin, G. V.; Gall, A. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 6 p. 648 - 653
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , # 6 p. 831 - 836
反应条件
hydrogen iodide T=100°C; 6 h; sealed ampoule;
参考文献
Shishkin, G. V.; Gall, A. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 6 p. 648 - 653
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , # 6 p. 831 - 836
