3-氨基-苯并[b]噻吩-2-羧酸乙酯合成路线

参考文献

BAELL, Jonathan Bayldon; STREET, Ian Philip; SLEEBS, Brad Edmund
Patent: WO2012/131297 A1, 2012 ;
Location in patent: Page/Page column 85 ;
WO 2012/131297 A1

623-51-8巯基乙酸乙酯+

612-24-82-硝基苯甲腈

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

参考文献

Romagnoli, Romeo; Baraldi, Pier Giovanni; Kimatrai Salvador, Maria; Preti, Delia; Aghazadeh Tabrizi, Mojgan; Bassetto, Marcella; Brancale, Andrea; Hamel, Ernest; Castagliuolo, Ignazio; Bortolozzi, Roberta; Basso, Giuseppe; Viola, Giampietro
Journal of Medicinal Chemistry, 2013 , vol. 56, # 6 p. 2606 - 2618

34761-11-02-腈基硫酚+

105-36-2溴乙酸乙酯

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

参考文献

Genevois-Borella, Arielle; Vuilhorgne, Marc; Mignani, Serge
Heterocycles, 2002 , vol. 57, # 2 p. 317 - 322

873-32-5邻氯苯腈+

623-51-8巯基乙酸乙酯

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

参考文献

Synthesis, , # 24 p. 4180 - 4186

34761-11-02-腈基硫酚+

685-87-0溴代丙二酸二乙酯

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯+

34761-13-2

参考文献

Journal of the Chemical Society [Section] C: Organic, , p. 3903 - 3906

7238-62-22-氯-4-甲基-1,3-噻唑-5-甲酸乙酯+

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

122945-83-9

参考文献

Russo, Filippo; Santagati, Andrea; Santagati, Maria; Caruso, Antonina; Leone, Maria Grazia; et al.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 91 - 96