反应条件
1: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 120 °C / |Inert atmosphere 2: potassium hydroxide; water / ethanol / |Reflux 3: 4-(N,N-dimethlyamino)pyridine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.33 h / 20 °C View Scheme
参考文献
LUPIN LIMITED; KULKARNI, Sanjeev Anant; MADAN, Sachin; JANA, Nirmal Kumar; TALE, Prashant Vitthalrao; CHEEMALA, Narasimha Murthy; MAHANGARE, Sachin Jaysing; VIDHATE, Prashant Popatrao; KULKARNI, Chaitanya Prabhakar; PATEL, Sapana Suresh; PATIL, Amolsing Dattu; ZADE, Seema Prabhakar; SHINDE, Rohan Mahadev; PALLE, Venkata P.; KAMBOJ, Rajender Kumar
Patent: US2013/178457 A1, 2013 ;
